Redox-Tunable Ring Expansion Enabled By A Single-Component Electrophilic Nitrogen Atom Synthon
Kelly, P.Q.; Keramati, N.; Kaplin, K.R.; Lynch-Colameta, T.; Phelan J.P.; Levin, M.D.

Submitted. Preprint Available.


Evidence for Dearomatizing Spirocyclization and Dynamic Effects in the Quasi-Stereospecific Nitrogen Deletion of Tetrahydroisoquinolines
Masson-Makdissi, J.; Lalisse, R.F.; Yuan, M.; Dherange, B.D.; Gutierrez, O.; Levin, M.D.

J. Am. Chem. Soc. 2024, ASAP

Driscoll, J.L.; Levin, M.D.

in Encyclopedia of Reagents for Organic Synthesis, 2024.

Retrosynthetic Simplicity
Levin, M.D.

Synlett, 2023, 34, A-D.

Carbon-to-nitrogen single-atom transmutation of azaarenes
Woo, J.; Stein, C.; Christian, A.H.; Levin, M.D.

Nature2023, 623, 77–82.

Aromatic Nitrogen Scanning by Ipso-Selective Nitrene Internalization
Pearson, T.J.; Shimazumi, R.; Driscoll, J.L.; Dherange, B.D.; Park, D.; Levin, M.D.

Science 2023381(6665), 1474-1479.

A Focus on 1-Azahomocubane: the New Kid on the Block
Elgindy, C.; Levin, M.D.

Chem. Sci. 2023, 14, 7608 – 7610.

Core-Labeling (Radio)Synthesis of Phenols
Lynch, C.F.; Downey,J.W.;  Zhang, Y.; Hooker, J.M.; Levin, M.D.

Org. Lett. 202325(9), 7230 – 7235.

Berger, K.J.; Dherange, B.D.; Morales, M.; Driscoll, J.L. Tarhan, A.K.; Levin, M.D.

Org. Syn. 2023100, 113-135.

Direct Deaminative Functionalization
Dherange,B.D.; Yuan,M.; Kelly, C.B.; Reiher, C.A.; Grosanu, C.; Berger,K.J.; Gutierrez, O.; Levin, M.D.

J. Am. Chem. Soc. 2023, 145(1), 17-24.

C−C Coupling through Nitrogen Deletion: Application to Library Synthesis
Holovach,S.; Melnykov, K.P.; Poroshyn, I.; Iminov, R.T.; Dudenko, D. Kondratov, I.; Levin, M.D.; Grygorenko, O.O.

Chem. Eur. J. 202329(4), e202203470.

Unified Access to Pyrimidines and Quinazolines Enabled by N-N Cleaving Carbon Atom Insertion
Hyland, E.E.; Kelly, P.Q.; McKillop, A.M.; Dherange, B.D.; Levin, M.D.

J. Am. Chem. Soc. 2022, 144(42), 19258–19264


A Synthetic Cycle for Heteroarene Synthesis by Nitride Insertion
Kelly, P.Q.; Filatov, A.S.; Levin, M.D.

Angew. Chem. Int. Ed. 2022, 61(46), e202213041.

Scaffold Hopping by Net Photochemical Carbon Deletion of Azaarenes
Woo, J.; Christian, A.H.; Burgess, S.A.; Jiang, Y.; Mansoor, U.F.; Levin, M.D.

Science, 2022376(6593), 527-532.


Single-Atom Logic for Heterocycle Editing
Jurczyk, J.; Woo, J.; Kim, S.F.; Dherange, B.D.; Sarpong, R.; Levin, M.D.

Nat. Synth. 2022,1, 352-364.

Direct Deamination of Primary Amines via Isodiazene Intermediates
Berger, K.J.; Driscoll, J.L.; Yuan, M.; Dherange, B.D.; Gutierrez, O.; Levin, M.D.

J. Am. Chem. Soc. 2021, 143(42), 17366–17373.

Carbon Atom Insertion into Pyrroles and Indoles Promoted by Chlorodiazirines
Dherange, B.D.; Kelly, P.Q.; Liles, J.P.; Sigman, M.S.; Levin, M.D.

J. Am. Chem. Soc. 2021, 143(30), 11337-11344

Skeletal Editing Through Direct Nitrogen Deletion of Secondary Amines
Kennedy, S.H.; Dherange, B.D.; Berger, K.J. Levin, M.D.

Nature2021593, 223–227.

Reframing Primary Alkyl Amines as Aliphatic Building Blocks
Berger, K.J; Levin, M.D. 

Org. Biomol. Chem. 202119, 11-36.

Prior to Chicago

Levin, M.D.; Ovian, J.M.; Read, J.A.; Sigman, M.S.; Jacobsen, E.N. Catalytic Enantioselective Synthesis of Difluorinated Alkyl Bromides.

J. Am. Chem. Soc. 2020, 142 (35), 14831.

Huang, B.; He, Y.; Levin, M.D.; Coelho, J.A.S.; Bergman, R.G.; Toste, F.D. Enantioselective Kinetic Resolution/Desymmetrization of Para-Quinols: A Case Study in Boronic-Acid-Directed Phosphoric Acid Catalysis.

Adv. Synth. Catal. 2020, 362 (2), 295.
(Eric Jacobsen 60th Birthday Special Issue)

Levin, M.D.; O’Neil, J.P.; Toste, F.D. Au(III) Complexes for [18F] Trifluoromethylation and Method for Preparation of the Same.

US 2018/033677, filed 21 May 2018.

Levin, M.D.; Chen, T.Q.; Neubig, M.; Theulier, C.A.; Hong, C.M.; O’Neil, J. P.; Toste, F.D. A Catalytic Fluoride-Rebound Mechanism for C(sp3)-CF3 Bond Formation.

Science 2017, 356 (6344), 1272.

Levin, M.D.*; Kaphan, D.M.*; Hong, C.M.; Bergman, R.G.; Raymond, K.N.; Toste, F.D. Scope and Mechanism of Cooperativity at the Intersection of Organometallic and Supramolecular Catalysis.

J. Am. Chem. Soc. 2016, 138 (30), 9682.

Levin, M.D.; Kim, S.; Toste, F.D. Photoredox Catalysis Unlocks Single-Electron Elementary Steps in Transition Metal Catalyzed Cross-Coupling. (Review)

ACS Cent. Sci., 2016, 2 (5), 293.

Kaphan, D.M.*; Levin, M.D.*; Bergman, R.G.; Raymond, K.N.; Toste, F.D. A Supramolecular Microenvironment Strategy for Transition Metal Catalysis.

Science 2015, 350 (6265), 1235.

Levin, M.D.; Toste, F.D. Gold-Catalyzed Allylation of Aryl Boronic Acids: Accessing Cross-Coupling Reactivity with Gold.

Angew. Chem. Int. Ed. 2014, 53, 6211

Spencer, W.T., III; Levin, M.D.; Frontier, A.J. Oxidation-Initiated Nazarov Cyclization of Vinyl Alkoxyallenes.

Org. Lett. 2011, 13, 414.